MOD 50 sounds great at any setting, volume, tube combination, power rating, wattage. No coplaints. The difference in the volume between the low and high power settings are hardly noticible, but you reach power tube saturation a litter earlier in low power.
It's not a dark or bright amp, that is the genius of it. If you want bright, put a Deluxe module in there with 6L6 tubes. Best Fender sound you will ever hear. If you want smack, put a Erect module in there. Change the tubes out to EL34 put and SL or SL++ or EG3/4 and youve got smooth and dark. Want to split the defference? Do like I do, run it with Tung Sol 5881 and get the best of evrything. I run mine with either Bassman or SL module and then a EG3/4.
The loops are very good. Line level devices are no problem, best results have been acheived with TC Electonics and Rocktron units or any multi effects unit that allows some of the uneffected signal to be mixed in with the effected signal, or use anything of good quality and run it through the parallel loop with mix knob on the front. People run into problems because they are not intended for use with pedals. They are forgiving enough to accomodate some/most pedals. But some pedals run at a level that does not work well. This is easily fixed by using an Ebtech line level matching device. I do this too. Works great.
Superb amplifiers, extreme flexability and really not very high prices when you consider they deliver unequaled tone and options with so many different modules and the option of a custom shop waiting to build and modify anything you want. It does not get any better IMHO.