The thing about 2x12s is this: a 4x12 is ideal in some ways (if you forget for a moment the weight and the ridiculous amount of volume it creates) because it gives you a couple of speakers on the ground, which fills out the low end and gives you that "chunk" we all love, and it also gives you a couple of speakers higher up, delivering some treble that has a better chance of making it to your ear. If you take a horizontal 2x12 and put it on the ground, you probably get most of your chunk, but all your treble is hitting your ankles. If you're not aware of this, you crank up the high end to compensate, and then your audience's ears start bleeding (because THEY'RE certainly getting all that treble). Put it up on a stand or a chair so you get a better sense of the treble, however, and your chunk disappears. That's why I prefer vertical 2x12s. I don't understand why they're generally rare in the marketplace. My Recto vertical 2x12 is the best cab I've ever had. Other guitar players gush about it to me all the time.